Cynthia K. Holland

Cynthia Holland

Assistant Professor of Biology

413-597-2746
Thompson Biology Lab
At Williams since 2020

Education

Ph.D. Washington University, Biology

Areas of Expertise

Biochemistry and Structural Biology

Scholarship/Creative Work

Selected publications:

Züst T, Strickler SR, Powell AF, Mabry ME, An H, Mirzaei M, York T, Holland CK, Kumar P, Erb M, Petschenka G, Gómez J-M, Perfectti F, Müller C, Pires JC, Mueller LA, Jander G (2020) Independent evolution of ancestral and novel defenses in a genus of toxic plants (Erysimum, Brassicaceae). eLife 9:e51712

Holland CK, Westfall CS, Schaffer JE, De Santiago A, Zubieta C, Alvarez S, Jez JM (2019) Brassicaceae-specific Gretchen Hagen 3 acyl acid amido synthetases conjugate amino acids to chorismate, a precursor of aromatic amino acids and salicylic acid.  J Biol Chem 294, 16855-64

Holland CK, Berkovich DA, Kohn ML, Maeda H, Jez JM (2018) Structural basis for substrate recognition and inhibition of prephenate aminotransferase from Arabidopsis.  Plant J 94, 304-14

Kroll K*, Holland CK*, Starks CM, Jez JM (2017) Evolution of allosteric regulation in chorismate mutases from early plants.  Biochem J 474, 3705-17. *Equal contribution

Schenck CA*, Holland CK*Schneider MR, Men Y, Lee SG, Jez JM, Maeda HA (2017) Molecular basis of the evolution of alternative tyrosine biosynthesis pathways in plants.  Nature Chem Biol 13, 1029-35. *Equal contribution

Awards, Fellowships & Grants

Journal of Biological Chemistry Early Career Reviewer

National Science Foundation Postdoctoral Research Fellowship

ASBMB Experimental Biology Travel Award

William H. Danforth Plant Sciences Fellow

National Science Foundation Graduate Research Fellow

American Society of Pharmacognosy Undergraduate Research Award

 

Professional Affiliations

American Society of Plant Biologists and Northeast Section

American Society of Biochemistry and Molecular Biology

American Association for the Advancement of Science